Research in the field of psychoneuroimmunology (PNI) demonstrates that negative emotional states, such as chronic stress, depression or anxiety, increase systemic inflammation. This effect increases the risk of cardiovascular disease, diabetes, Alzheimer's, cancer and other illnesses. Below is a great quick overview, with links to many more articles in this field.

Maes, M. (2001). Psychological stress and the inflammatory response system. Clinical Science, 101, 193-194 [click here].

See also
Psychoneuroimmunology Home Page
Book Review
The Psychoneuroimmunology of Chronic Disease
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